Secure What Matters:
Your Gut Microbiome
Kryobiom® helps effectively restore your gut microbiome by utilizing your own microorganisms. Maintain your current microbial balance today to recover more quickly and feel better in the future.
What sets Kryobiom® apart
Natural
Kryobiom® is made entirely from your own microorganisms.
Effective
Studies show high success rates in restoring the gut microbiome.¹1
Fast
After antibiotic treatment, the gut microbiome recovers significantly faster when your own microorganisms are reintroduced.2
Personal
An individualized medicinal product manufactured according to pharmaceutical standards — scientifically validated.3
The Microbiome as the Foundation of Our Well-Being
Our microbiome consists of billions of beneficial microorganisms. When balanced, it strengthens the immune system, supports digestion, and stabilizes metabolic processes.
Antibiotics, surgery, infections, stress, or an unhealthy diet can disrupt this sensitive ecosystem
Possible consequences of microbiome disruption include increased susceptibility to infections, digestive issues, fatigue, skin problems, and other health issues.
The Problem with Conventional Probiotics
Every person’s gut microbiome is unique — like a fingerprint.
Conventional probiotics, however, contain only a limited selection of bacterial strains. They cannot fully replace the diversity of an individual microbiome and often provide only partial support.
Crucial for effective regeneration:
A microbiome composition that precisely matches your own restores balance far more effectively than any standardized product.
The Solution
Kryobiom® uses your own gut microbiome to create an individualized medicinal product. If needed, your original microbial balance is immediately available again.
With just a single administration, your gut regains its familiar microbial diversity in a short time. It quickly returns to its natural balance — in a completely natural way.
Get Free Information
Do you have questions about Kryobiom® or would you like to learn more?
Feel free to contact us for a personal information appointment.
Compelling Evidence of Effectiveness
Sustained Impact
Studies show that the diversity of the gut microbiome can be maintained long-term through the reintroduction of one’s own microorganisms.4
Broad Applicability
The effectiveness of this approach has been investigated and confirmed in numerous international studies.5
Natural Balance
By reintroducing your own microorganisms, the gut microbiome can largely return to its original balance.6
Clinically Tested
Multiple international studies demonstrate the feasibility and safety of the procedure.7
How It Works
1
At a time when your gut microbiome is healthy, microorganisms are isolated from stool material.
2
The microorganisms are tested for pathogens, carefully processed, and deep-frozen in capsules.
3
If your gut microbiome becomes disrupted later on, a single administration of Kryobiom® is usually sufficient.
4
Kryobiom® uses your own microorganisms to restore the natural balance of your gut microbiome quickly and effectively.
How It Works
1
2
3
4
At a time when your gut microbiome is healthy, microorganisms are isolated from stool material.
The microorganisms are tested for pathogens, carefully processed, and deep-frozen in capsules.
If your gut microbiome becomes disrupted later on, a single administration of Kryobiom® is usually sufficient.
Kryobiom® uses your own microorganisms to restore the natural balance of your gut microbiome quickly and effectively.
How It Works
1
2
3
4
At a time when your gut microbiome is healthy, microorganisms are isolated from stool material.
The microorganisms are tested for pathogens, carefully processed, and deep-frozen in capsules.
If your gut microbiome becomes disrupted later on, a single administration of Kryobiom® is usually sufficient.
Kryobiom® uses your own microorganisms to restore the natural balance of your gut microbiome quickly and effectively.
The Person Behind Kryobiom®
I am Dr. Johannes Sturm, a specialist in Internal Medicine with extensive experience in treating digestive disorders and preventive medicine. My focus lies on promoting gut health and the targeted use of the microbiome — which ultimately led to the development of Kryobiom®
I combine modern evidence-based medicine with scientifically grounded, holistic approaches to provide every patient with individualized and sustainable care.
Personal consultation is essential to me: through detailed discussions and thorough examinations, I identify the underlying causes of symptoms and provide precise, targeted treatment.
When Kryobiom® Can Be Used
Frequent Infections
Helps restore and rebalance the gut microbiome after antibiotics have disrupted it.
Before and After Surgery
Supports the gut microbiome in recovering more quickly from the stresses associated with surgical procedures.
Preventive Use
Preserves your gut microbiome for the coming months — in case it becomes disrupted by illness or medication.
Sports and an Active Lifestyle
Helps stabilize and rebalance the gut microbiome after intense training phases, frequent infections, or the use of medication.
Long-term Preservation
Preservation of your gut microbiome at −130 °C for up to 30 years.
Described by Harvard Medical School as the concept of a Microbiome Ark.8
Langzeitsicherung
Sicherung der Darmflora bei −130 °C bis zu 30 Jahre. Von der Harvard Medical School als Microbiome Ark beschrieben.8
Is Kryobiom® right for me?
This tool helps you assess whether Kryobiom may be a meaningful option in your situation. It does not replace personal medical advice, but gives you an initial overview – and if you wish, you can directly schedule a consultation.
Which statements apply to you? (Multiple selection possible)
Short medical safety check
Please note: This decision aid is intended for general orientation only and cannot replace an individual medical consultation. Whether Kryobiom® is appropriate for you in your specific case will be clarified together in a personal consultation.
Have more questions?
Here you can find additional information and answers about Kryobiom®.
Secure Your Gut Microbiome – in 4 Steps
Einfach und komfortabel: Für die Vorbereitung und Anwendung von Kryobiom® sind nur zwei Praxisbesuche notwendig.
So laufen die Schritte im Detail ab.
During the initial medical consultation – on-site or via video –
we discuss your personal situation, medical history, and potential use cases for Kryobiom®. You receive clear information about the procedure, benefits, and limitations.
Why this step matters
- It clarifies whether microbiota preservation is meaningful in your situation.
- You receive an individual medical assessment before making a decision.
- Questions and possible alternatives are openly addressed.
You provide your stool sample at my practice in Nuremberg.
During this visit, a blood sample is taken to check blood count and inflammatory markers and to rule out specific infectious diseases.
In addition, the stool sample is analyzed by PCR for 22 selected pathogenic organisms. Your microbiota is preserved only if all findings are unremarkable.
Why this step matters
- Your microbiota is preserved only if none of the tested pathogens are detected.
- Blood markers and PCR testing help identify acute infections.
- This ensures a safe basis for processing and long-term preservation.
The microorganisms contained in your stool sample are isolated and processed according to pharmaceutical Good Manufacturing Practice (GMP) standards.
Afterwards, capsules are produced that contain your individual gut microbiota.
Why this step matters
- You receive an individual medicinal product – manufactured exclusively from your own microorganisms.
- GMP-compliant processing ensures quality and safety.
- Only through this process can a later re-administration be performed in an effective form.
The Kryobiom® capsules are stored at −80 °C.
Additionally, you have the option of long-term storage at −130 °C for up to 30 years. This option opens new perspectives for future applications.
If your gut microbiome becomes impaired within 9 months (e.g., due to antibiotics or illness), re-administration can be performed – usually a single dose is sufficient.
⚠️ Important Note: Re-administration is currently only allowed within 9 months.
Studies on extended stability are ongoing. All users will be informed as soon as longer re-administration intervals are officially approved.
Why this step matters
- You have an immediately available backup of your own microorganisms for 9 months.
- Storage at −130 °C enables long-term preservation for up to 30 years.
- Ongoing studies open the perspective for extended re-administration options.
Secure Your Gut Microbiome – in 4 Steps
Simple and convenient: Preparing and applying Kryobiom® requires only two practice visits.
Here is a detailed explanation of the process.
1 Initial Consultation
During the initial medical consultation – on-site or via video –
we discuss your personal situation, medical history, and potential use cases for Kryobiom®.
You receive clear information about the procedure, benefits, and limitations.
Why this step matters
- It clarifies whether microbiota preservation is meaningful in your situation.
- You receive an individual medical assessment before making a decision.
- Questions and possible alternatives are openly addressed.
2 Sample Collection and Testing
You provide your stool sample at my practice in Nuremberg.
During this visit, a blood sample is taken to check blood count and inflammatory markers and to rule out specific infectious diseases.
In addition, the stool sample is analyzed by PCR for 22 selected pathogenic organisms.
Your microbiota is preserved only if all findings are unremarkable.
Why this step matters
- Your microbiota is preserved only if none of the tested pathogens are detected.
- Blood markers and PCR testing help identify acute infections.
- This ensures a safe basis for processing and long-term preservation.
3 Processing
The microorganisms contained in your stool sample are isolated and processed according to pharmaceutical Good Manufacturing Practice (GMP) standards.
Afterwards, capsules are produced that contain your individual gut microbiota.
Why this step matters
- You receive an individual medicinal product – manufactured exclusively from your own microorganisms.
- GMP-compliant processing ensures quality and safety.
- Only through this process can a later re-administration be performed in an effective form.
4 Storage and Re-Administration
The Kryobiom® capsules are stored at −80 °C.
Additionally, you have the option of long-term storage at −130 °C for up to 30 years.
This option opens new perspectives for future applications.
If your gut microbiome becomes impaired within 9 months
(e.g., due to antibiotics or illness), re-administration can be performed –
usually a single dose is sufficient.
⚠️ Important Note: Re-administration is currently only allowed within 9 months.
Studies on extended stability are ongoing.
All users will be informed as soon as longer re-administration intervals are officially approved.
Why this step matters
- You have an immediately available backup of your own microorganisms for 9 months.
- Storage at −130 °C enables long-term preservation for up to 30 years.
- Ongoing studies open the perspective for extended re-administration options.
Are you planning to travel from farther away?
Here you will find helpful information and recommendations to make your visit as smooth and comfortable as possible.
Information for Medical Professionals
Everything about the development and research of Kryobiom®, an overview of the current clinical evidence, and insights into the methods used for preparation and storage.
I’m here to help.
Whether on-site or virtual – personal and individual consultation is essential for any treatment. Feel free to schedule a non-binding initial consultation or contact me if you have any questions.
1 Zain NM, et al. Design and manufacture of a lyophilised faecal microbiota capsule formulation to GMP standards. J Control Release. 2022;345:240–248. https://pubmed.ncbi.nlm.nih.gov/35963468/
van Nood E, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med. 2013;368(5):407–415. https://pubmed.ncbi.nlm.nih.gov/23323867/
2 Suez J, et al. Post-Antibiotic Gut Mucosal Microbiome Reconstitution is Impaired by Probiotics and Improved by Autologous FMT. Cell. 2018;174(6):1406–1423.e16. https://www.cell.com/cell/fulltext/S0092-8674(18)31108-5
3 Zain NM, et al. Design and manufacture of a lyophilised faecal microbiota capsule formulation… J Control Release. 2022;345:240–248. https://pubmed.ncbi.nlm.nih.gov/35963468/
Reygner J, et al. Stool storage conditions for fecal microbiota transplantation: biological activity maintained up to 12 months. Gut Microbes. 2020;12(1):1–13. https://pmc.ncbi.nlm.nih.gov/articles/PMC9284506/
Burz SD, et al. Cryopreservation and revival of fecal microbiota reduce viability and alter bacterial composition. Sci Rep. 2019;9:7007. https://www.nature.com/articles/s41598-019-45173-4
4 Rinott E, et al. Effects of diet-modulated autologous fecal microbiota transplantation on weight regain. Gastroenterology. 2021;160(1):158–173.e10. https://pubmed.ncbi.nlm.nih.gov/32860791/
5 Taur Y, et al. Gut microbiota diversity after autologous fecal microbiota transfer in acute myeloid leukemia patients. Nat Commun. 2021;12:4923. https://www.nature.com/articles/s41467-021-23376-6
Qayed M, et al. Autologous fecal microbiota transplantation to improve outcomes of hematopoietic stem cell transplantation: Results of a single-centre feasibility study. Biomedicines. 2023;11(12):3274. https://www.mdpi.com/2227-9059/11/12/3274
Liu Z, et al. Pilot study of autologous fecal microbiota transplants in nursing home residents: Feasibility and safety. Contemp Clin Trials Commun. 2022;27:100913. https://www.sciencedirect.com/science/article/pii/S2451865422000230
6 Suez J, et al. Post-Antibiotic Gut Mucosal Microbiome Reconstitution… Cell. 2018;174(6):1406–1423.e16. https://www.cell.com/cell/fulltext/S0092-8674(18)31108-5
7 see references 4 und 5
8 Ke S, Weiss ST, Liu YY. Rejuvenating the human gut microbiome. Trends Mol Med. 2022 Aug;28(8):619-630. doi: 10.1016/j.molmed.2022.05.005. Epub 2022 Jun 30. PMID: 35781423; PMCID: PMC9339459. https://pmc.ncbi.nlm.nih.gov/articles/PMC9339459/